Use this option and download Media Creation Tool if you want to create bootable USB media to perform a clean install on new or existing hardware. To get started you first need a license to install Windows 11 or have a Windows 10 device that qualifies for an upgrade to Windows 11.
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To get started, you will first need to have a license to install Windows 11. You can then download and run the media creation tool. For more information on how to use the tool, see the instructions below.
The new E-Prime 3 Experiment Library includes completed experiments that can be downloaded to use and/or modify. Examples of how to perform specific actions in your experiment are available in our Samples area.
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Hybrid Analysis requires that users undergo the Hybrid Analysis Vetting Process prior to obtaining an API key or downloading malware samples. Please note that you must abide by the Hybrid Analysis Terms and Conditions and only use these samples for research purposes. You are not permitted to share your user credentials or API key with anyone else. Please notify Hybrid Analysis immediately if you believe that your API key or user credentials have been compromised.
A novel core-shell DNA self-assembly catalyzed by thiol-disulfide exchange reactions was proposed, which could realize GSH-initiated hybridization chain reaction (HCR) for signal amplification and molecules gathering. Significantly, these self-assembled products via electrostatic interaction could accumulate into prominent and clustered fluorescence-bright spots in single cancer cells for reduced glutathione monitoring, which will effectively drive cell monitoring into a new era.
Inspired by that mentioned above, we proposed a core-shell DNA self-assembly catalyzed via thiol-disulfide exchange reactions that could realize target-initiated hybridization chain reaction (HCR) for reduced glutathione detection. Importantly, a non-destructive signal amplification tactic for GSH monitoring in living cells was developed. This core-shell self-assembly had a nuclear nanosphere and an outer layer of fluorogen-labeled nucleic acid congeries, attributed to the HCR products triggered via thiol-disulfide exchange reactions. The intracellular core-congeries supplied efficient signal enlargement, fluorescence gathering and enabled super-sensitive monitoring of GSH levels. Moreover, in situ imaging of GSH in living cells could boost the monitoring of the distribution and dynamical expression of GSH and research on GSH-related cellular processes and diseases.
This work reported a novel core-shell DNA self-assembly catalyzed by thiol-disulfide exchange reactions, which could realize target-initiated hybridization chain reaction for signal amplification and molecules gathering. Significantly, the self-assembled core-congeries could accumulate into prominent and clustered fluorescence-bright spots in single cancer cells for GSH monitoring. This finding has exciting potential in the study of pathological variations or biological processes in live cells in virtue of its good selectivity and excellent sensitivity.
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VMware is offering a free download of VMware Tanzu Kubernetes Grid in place of VMware Tanzu Community Edition software and is retiring Tanzu Community Edition. Use Tanzu Kubernetes Grid for free in non-commercial environments up to 100 cores.
Acting on insights gained through community engagement over the past year, VMware has decided to offer a free download of VMware Tanzu Kubernetes Grid in place of VMware Tanzu Community Edition software and to retire the Tanzu Community Edition open source project. Users can download Tanzu Kubernetes Grid here.
Cloud native practitioners value free and easy access to a version of Tanzu software with which they can experiment and explore. Tanzu Kubernetes Grid, available as a free download, offers a conformant Kubernetes runtime solution built on open source, offers capabilities similar to Tanzu Community Edition, and provides a frictionless upgrade path to commercial Tanzu offerings.
Freely available Tanzu Kubernetes Grid has replaced Tanzu Community Edition for anyone wanting to learn about, evaluate, or use Tanzu runtime for non-commercial use up to 100 core environments. Interested users can download Tanzu Kubernetes Grid and take advantage of the many free resources available to them like Tanzu Developer Center and Tanzu Tech Zone, which include informative articles, guides, videos, samples, workshops, and more.
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